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HEXIM1 controls P-TEFb processing and regulates drug sensitivity in triple-negative breast cancer

The positive transcription elongation factor b (P-TEFb), composed of CDK9 and cyclin T, stimulates transcriptional elongation by RNA polymerase (Pol) II and regulates cell growth and differentiation. Recently, we demonstrated that P-TEFb also controls the expression of EMT regulators to promote brea...

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Detalhes bibliográficos
Publicado no:Mol Biol Cell
Main Authors: Shao, Hengyi, Zhu, Qingwei, Lu, Huasong, Chang, Amanda, Gao, Carol, Zhou, Qiang, Luo, Kunxin
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Cell Biology 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7525814/
https://ncbi.nlm.nih.gov/pubmed/32520633
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E19-12-0704
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