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HEXIM1 controls P-TEFb processing and regulates drug sensitivity in triple-negative breast cancer
The positive transcription elongation factor b (P-TEFb), composed of CDK9 and cyclin T, stimulates transcriptional elongation by RNA polymerase (Pol) II and regulates cell growth and differentiation. Recently, we demonstrated that P-TEFb also controls the expression of EMT regulators to promote brea...
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| Veröffentlicht in: | Mol Biol Cell |
|---|---|
| Hauptverfasser: | , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
The American Society for Cell Biology
2020
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7525814/ https://ncbi.nlm.nih.gov/pubmed/32520633 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E19-12-0704 |
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