Tat competes with HEXIM1 to increase the active pool of P-TEFb for HIV-1 transcription

Human immunodeficiency virus type 1 (HIV-1) transcriptional transactivator (Tat) recruits the positive transcription elongation factor b (P-TEFb) to the viral promoter. Consisting of cyclin dependent kinase 9 (Cdk9) and cyclin T1, P-TEFb phosphorylates RNA polymerase II and the negative transcriptio...

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Autors principals: Barboric, Matjaz, Yik, Jasper H. N., Czudnochowski, Nadine, Yang, Zhiyuan, Chen, Ruichuan, Contreras, Xavier, Geyer, Matthias, Matija Peterlin, B., Zhou, Qiang
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2007
Matèries:
Molecular Biology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1874611/
https://ncbi.nlm.nih.gov/pubmed/17341462
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkm063
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