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LARP7 suppresses P-TEFb activity to inhibit breast cancer progression and metastasis
Transcriptional elongation by RNA polymerase (Pol) II is essential for gene expression during cell growth and differentiation. The positive transcription elongation factor b (P-TEFb) stimulates transcriptional elongation by phosphorylating Pol II and antagonizing negative elongation factors. A reser...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
eLife Sciences Publications, Ltd
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4126343/ https://ncbi.nlm.nih.gov/pubmed/25053741 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.02907 |
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