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An IFT20 mechanotrafficking axis is required for integrin recycling, focal adhesion dynamics, and polarized cell migration

Directional cell migration drives embryonic development, cancer metastasis, and tissue repair and regeneration. Here, we examine the role of intraflagellar transport (IFT) 20 (Ift20) during polarized migration of epidermal cells. IFT20 is implicated in regulating cell migration independently of the...

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Détails bibliographiques
Publié dans:Mol Biol Cell
Auteurs principaux: Su, Steven, Begum, Salma, Ezratty, Ellen J.
Format: Artigo
Langue:Inglês
Publié: The American Society for Cell Biology 2020
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7525813/
https://ncbi.nlm.nih.gov/pubmed/32520638
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E20-04-0232
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