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An IFT20 mechanotrafficking axis is required for integrin recycling, focal adhesion dynamics, and polarized cell migration

Directional cell migration drives embryonic development, cancer metastasis, and tissue repair and regeneration. Here, we examine the role of intraflagellar transport (IFT) 20 (Ift20) during polarized migration of epidermal cells. IFT20 is implicated in regulating cell migration independently of the...

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Bibliografske podrobnosti
izdano v:Mol Biol Cell
Main Authors: Su, Steven, Begum, Salma, Ezratty, Ellen J.
Format: Artigo
Jezik:Inglês
Izdano: The American Society for Cell Biology 2020
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7525813/
https://ncbi.nlm.nih.gov/pubmed/32520638
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E20-04-0232
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