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An IFT20 mechanotrafficking axis is required for integrin recycling, focal adhesion dynamics, and polarized cell migration

Directional cell migration drives embryonic development, cancer metastasis, and tissue repair and regeneration. Here, we examine the role of intraflagellar transport (IFT) 20 (Ift20) during polarized migration of epidermal cells. IFT20 is implicated in regulating cell migration independently of the...

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Библиографические подробности
Опубликовано в: :Mol Biol Cell
Главные авторы: Su, Steven, Begum, Salma, Ezratty, Ellen J.
Формат: Artigo
Язык:Inglês
Опубликовано: The American Society for Cell Biology 2020
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7525813/
https://ncbi.nlm.nih.gov/pubmed/32520638
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E20-04-0232
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