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The ‘in vivo lifestyle’ of bile acid 7α-dehydroxylating bacteria: comparative genomics, metatranscriptomic, and bile acid metabolomics analysis of a defined microbial community in gnotobiotic mice

The formation of secondary bile acids by gut microbes is a current topic of considerable biomedical interest. However, a detailed understanding of the biology of anaerobic bacteria in the genus Clostridium that are capable of generating secondary bile acids is lacking. We therefore sought to determi...

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Veröffentlicht in:Gut Microbes
Hauptverfasser: Ridlon, Jason M., Devendran, Saravanan, Alves, João Mp, Doden, Heidi, Wolf, Patricia G., Pereira, Gabriel V., Ly, Lindsey, Volland, Alyssa, Takei, Hajime, Nittono, Hiroshi, Murai, Tsuyoshi, Kurosawa, Takao, Chlipala, George E., Green, Stefan J., Hernandez, Alvaro G., Fields, Christopher J., Wright, Christy L., Kakiyama, Genta, Cann, Isaac, Kashyap, Purna, McCracken, Vance, Gaskins, H. Rex
Format: Artigo
Sprache:Inglês
Veröffentlicht: Taylor & Francis 2019
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7524365/
https://ncbi.nlm.nih.gov/pubmed/31177942
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/19490976.2019.1618173
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