Proinflammatory intervertebral disc cell and organ culture models induced by tumor necrosis factor alpha

Inflammation plays an important role in the pathogenesis of intervertebral disc (IVD) degeneration. The proinflammatory cytokine tumor necrosis factor alpha (TNF‐α) has shown markedly higher expression in degenerated human disc tissue compared with healthy controls. Anti‐inflammatory treatment targe...

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Salvato in:
Dettagli Bibliografici
Pubblicato in:JOR Spine
Autori principali: Du, Jie, Pfannkuche, Judith‐J., Lang, Gernot, Häckel, Sonja, Creemers, Laura B., Alini, Mauro, Grad, Sibylle, Li, Zhen
Natura: Artigo
Lingua:Inglês
Pubblicazione: John Wiley & Sons, Inc. 2020
Soggetti:
Protocols, Methods, and Resources
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7524256/
https://ncbi.nlm.nih.gov/pubmed/33015577
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jsp2.1104
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