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Proinflammatory intervertebral disc cell and organ culture models induced by tumor necrosis factor alpha

Inflammation plays an important role in the pathogenesis of intervertebral disc (IVD) degeneration. The proinflammatory cytokine tumor necrosis factor alpha (TNF‐α) has shown markedly higher expression in degenerated human disc tissue compared with healthy controls. Anti‐inflammatory treatment targe...

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Detalhes bibliográficos
Publicado no:JOR Spine
Main Authors: Du, Jie, Pfannkuche, Judith‐J., Lang, Gernot, Häckel, Sonja, Creemers, Laura B., Alini, Mauro, Grad, Sibylle, Li, Zhen
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley & Sons, Inc. 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7524256/
https://ncbi.nlm.nih.gov/pubmed/33015577
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jsp2.1104
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