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Isolation of high‐quality RNA from intervertebral disc tissue via pronase predigestion and tissue pulverization

The isolation of high‐quality RNA from the intervertebral disc and especially from the nucleus pulposus is challenging due to the low cellularity and high proteoglycan content of this tissue. In this study, we report a simple modification of the standard guanidinium thiocyanate‐phenol‐chloroform ext...

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Dettagli Bibliografici
Pubblicato in:JOR Spine
Autori principali: Caprez, Stephanie, Menzel, Ursula, Li, Zhen, Grad, Sibylle, Alini, Mauro, Peroglio, Marianna
Natura: Artigo
Lingua:Inglês
Pubblicazione: John Wiley & Sons, Inc. 2018
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6686795/
https://ncbi.nlm.nih.gov/pubmed/31463444
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jsp2.1017
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