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Isolation of high‐quality RNA from intervertebral disc tissue via pronase predigestion and tissue pulverization

The isolation of high‐quality RNA from the intervertebral disc and especially from the nucleus pulposus is challenging due to the low cellularity and high proteoglycan content of this tissue. In this study, we report a simple modification of the standard guanidinium thiocyanate‐phenol‐chloroform ext...

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Bibliografiske detaljer
Udgivet i:JOR Spine
Main Authors: Caprez, Stephanie, Menzel, Ursula, Li, Zhen, Grad, Sibylle, Alini, Mauro, Peroglio, Marianna
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley & Sons, Inc. 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6686795/
https://ncbi.nlm.nih.gov/pubmed/31463444
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jsp2.1017
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