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Isolation of high‐quality RNA from intervertebral disc tissue via pronase predigestion and tissue pulverization

The isolation of high‐quality RNA from the intervertebral disc and especially from the nucleus pulposus is challenging due to the low cellularity and high proteoglycan content of this tissue. In this study, we report a simple modification of the standard guanidinium thiocyanate‐phenol‐chloroform ext...

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Dades bibliogràfiques
Publicat a:JOR Spine
Autors principals: Caprez, Stephanie, Menzel, Ursula, Li, Zhen, Grad, Sibylle, Alini, Mauro, Peroglio, Marianna
Format: Artigo
Idioma:Inglês
Publicat: John Wiley & Sons, Inc. 2018
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6686795/
https://ncbi.nlm.nih.gov/pubmed/31463444
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jsp2.1017
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