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Proinflammatory intervertebral disc cell and organ culture models induced by tumor necrosis factor alpha

Inflammation plays an important role in the pathogenesis of intervertebral disc (IVD) degeneration. The proinflammatory cytokine tumor necrosis factor alpha (TNF‐α) has shown markedly higher expression in degenerated human disc tissue compared with healthy controls. Anti‐inflammatory treatment targe...

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Bibliografski detalji
Izdano u:JOR Spine
Glavni autori: Du, Jie, Pfannkuche, Judith‐J., Lang, Gernot, Häckel, Sonja, Creemers, Laura B., Alini, Mauro, Grad, Sibylle, Li, Zhen
Format: Artigo
Jezik:Inglês
Izdano: John Wiley & Sons, Inc. 2020
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7524256/
https://ncbi.nlm.nih.gov/pubmed/33015577
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jsp2.1104
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