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Proinflammatory intervertebral disc cell and organ culture models induced by tumor necrosis factor alpha

Inflammation plays an important role in the pathogenesis of intervertebral disc (IVD) degeneration. The proinflammatory cytokine tumor necrosis factor alpha (TNF‐α) has shown markedly higher expression in degenerated human disc tissue compared with healthy controls. Anti‐inflammatory treatment targe...

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Detalles Bibliográficos
Publicado en:JOR Spine
Main Authors: Du, Jie, Pfannkuche, Judith‐J., Lang, Gernot, Häckel, Sonja, Creemers, Laura B., Alini, Mauro, Grad, Sibylle, Li, Zhen
Formato: Artigo
Idioma:Inglês
Publicado: John Wiley & Sons, Inc. 2020
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7524256/
https://ncbi.nlm.nih.gov/pubmed/33015577
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jsp2.1104
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