Lower DNA methylation levels in CpG island shores of CR1, CLU, and PICALM in the blood of Japanese Alzheimer’s disease patients

The aim of the present study was to (1) investigate the relationship between late-onset Alzheimer’s disease (AD) and DNA methylation levels in six of the top seven AD-associated genes identified through a meta-analysis of recent genome wide association studies, APOE, BIN1, PICALM, CR1, CLU, and ABCA...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Mitsumori, Risa, Sakaguchi, Kazuya, Shigemizu, Daichi, Mori, Taiki, Akiyama, Shintaro, Ozaki, Kouichi, Niida, Shumpei, Shimoda, Nobuyoshi
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2020
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7523949/
https://ncbi.nlm.nih.gov/pubmed/32991610
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0239196
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