Lower DNA methylation levels in CpG island shores of CR1, CLU, and PICALM in the blood of Japanese Alzheimer’s disease patients

The aim of the present study was to (1) investigate the relationship between late-onset Alzheimer’s disease (AD) and DNA methylation levels in six of the top seven AD-associated genes identified through a meta-analysis of recent genome wide association studies, APOE, BIN1, PICALM, CR1, CLU, and ABCA...

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Veröffentlicht in:PLoS One
Hauptverfasser: Mitsumori, Risa, Sakaguchi, Kazuya, Shigemizu, Daichi, Mori, Taiki, Akiyama, Shintaro, Ozaki, Kouichi, Niida, Shumpei, Shimoda, Nobuyoshi
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2020
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7523949/
https://ncbi.nlm.nih.gov/pubmed/32991610
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0239196
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