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Decrease in cytosine methylation at CpG island shores and increase in DNA fragmentation during zebrafish aging
Age-related changes in DNA methylation have been demonstrated in mammals, but it remains unclear as to the generality of this phenomenon in vertebrates, which is a criterion for the fundamental cause of senescence. Here we showed that the zebrafish genome gradually and clearly lost methylcytosine in...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Springer Netherlands
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3889898/ https://ncbi.nlm.nih.gov/pubmed/23736955 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11357-013-9548-5 |
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