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MicroRNA-Independent Modulation of DICER1 Expression by hAgo2

Many proteins, including DICER1 and hAgo2, are involved in the biogenesis of microRNAs (miRNAs). Whether hAgo2 regulates DICER1 expression is unknown. Exogenously overexpressed hAgo2 suppressed DICER1 expression at the levels of both protein and mRNA, and the reduction in hAgo2 expression enhanced D...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Mol Cell Biol
Hauptverfasser: Yang, Chee-Hing, Li, Hui-Chun, Ku, Tzu-Shan, Wu, Cheng-Hao, Sim, Kei-Choon, Lo, Shih-Yen
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2020
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7523658/
https://ncbi.nlm.nih.gov/pubmed/32778571
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00221-20
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