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MicroRNA-Independent Modulation of DICER1 Expression by hAgo2

Many proteins, including DICER1 and hAgo2, are involved in the biogenesis of microRNAs (miRNAs). Whether hAgo2 regulates DICER1 expression is unknown. Exogenously overexpressed hAgo2 suppressed DICER1 expression at the levels of both protein and mRNA, and the reduction in hAgo2 expression enhanced D...

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Detalhes bibliográficos
Publicado no:Mol Cell Biol
Main Authors: Yang, Chee-Hing, Li, Hui-Chun, Ku, Tzu-Shan, Wu, Cheng-Hao, Sim, Kei-Choon, Lo, Shih-Yen
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7523658/
https://ncbi.nlm.nih.gov/pubmed/32778571
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00221-20
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