Conserved vertebrate mir-451 provides a platform for Dicer-independent, Ago2-mediated microRNA biogenesis

Canonical animal microRNAs (miRNAs) are generated by sequential cleavage of precursor substrates by the Drosha and Dicer RNase III enzymes. Several variant pathways exploit other RNA metabolic activities to generate functional miRNAs. However, all of these pathways culminate in Dicer cleavage, sugge...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Yang, Jr-Shiuan, Maurin, Thomas, Robine, Nicolas, Rasmussen, Kasper D., Jeffrey, Kate L., Chandwani, Rohit, Papapetrou, Eirini P., Sadelain, Michel, O'Carroll, Dónal, Lai, Eric C.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: National Academy of Sciences 2010
विषय:
Biological Sciences
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC2930549/
https://ncbi.nlm.nih.gov/pubmed/20699384
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1006432107
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