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A Dicer-independent miRNA biogenesis pathway that requires Ago catalysis
The nucleolytic activity of animal Argonaute proteins is deeply conserved, despite its having no obvious role in microRNA-directed gene regulation. In mice, Ago2 (also known as Eif2c2) is uniquely required for viability, and only this family member retains catalytic competence. To investigate the ev...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2010
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2995450/ https://ncbi.nlm.nih.gov/pubmed/20424607 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature09092 |
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