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Highly Selective β-Mannosylations and β-Rhamnosylations Catalyzed by a Bis-thiourea

We report highly β-selective bis-thiourea-catalyzed 1,2-cis-O-pyranosylations employing easily accessible acetonide-protected donors. A wide variety of alcohol nucleophiles, including complex natural products, glycosides, and amino acids were β-mannosylated and rhamnosylated successfully using an op...

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Библиографические подробности
Опубликовано в: :J Am Chem Soc
Главные авторы: Li, Qiuhan, Levi, Samuel M., Jacobsen, Eric N.
Формат: Artigo
Язык:Inglês
Опубликовано: 2020
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7523191/
https://ncbi.nlm.nih.gov/pubmed/32527078
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.0c04255
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