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Thiourea-Catalyzed Enantioselective Cyanosilylation of Ketones

[Image: see text] The new chiral amino thiourea catalyst 3d promotes the highly enantioselective cyanosilylation of a wide variety of ketones. The hindered tertiary amine substituent plays a crucial role both with regard to stereoinduction and reactivity, suggesting a cooperative mechanism involving...

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Bibliografiske detaljer
Main Authors: Fuerst, Douglas E., Jacobsen, Eric N.
Format: Artigo
Sprog:Inglês
Udgivet: 2005
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3166885/
https://ncbi.nlm.nih.gov/pubmed/15969569
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja052511x
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