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Enantioselective Thiourea-Catalyzed Intramolecular Cope-Type Hydroamination

Catalysis of Cope-type rearrangements of bishomoallylic hydroxylamines is demonstrated using chiral thiourea derivatives. This formal intramolecular hydroamination reaction provides access to highly enantioenriched α-substituted pyrrolidine products, and represents a complementary approach to metal-...

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Bibliografske podrobnosti
Main Authors: Brown, Adam R., Uyeda, Christopher, Brotherton, Carolyn A., Jacobsen, Eric N.
Format: Artigo
Jezik:Inglês
Izdano: 2013
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3689223/
https://ncbi.nlm.nih.gov/pubmed/23597402
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja402893z
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