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A natural mutation between SARS-CoV-2 and SARS-CoV determines neutralization by a cross-reactive antibody
Epitopes that are conserved among SARS-like coronaviruses are attractive targets for design of cross-reactive vaccines and therapeutics. CR3022 is a SARS-CoV neutralizing antibody to a highly conserved epitope on the receptor binding domain (RBD) on the spike protein that can cross-react with SARS-C...
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| 發表在: | bioRxiv |
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| Main Authors: | , , , , , , , , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Cold Spring Harbor Laboratory
2020
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7523114/ https://ncbi.nlm.nih.gov/pubmed/32995788 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/2020.09.21.305441 |
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