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15-Deoxy-Δ(12,14)-prostaglandin J(2) Induces Epithelial-to-mesenchymal Transition in Human Breast Cancer Cells and Promotes Fibroblast Activation
In inflammation-associated carcinogenesis, COX-2 is markedly overexpressed, resulting in accumulation of various prostaglandins. 15-deoxy-Δ(12,14)-prostaglandin J(2) (15d-PGJ(2)) is one of the terminal products of COX-2-catalyzed arachidonic acid catabolism with oncogenic potential. Epithelial-to-me...
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| 發表在: | J Cancer Prev |
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| Main Authors: | , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Korean Society of Cancer Prevention
2020
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7523036/ https://ncbi.nlm.nih.gov/pubmed/33033709 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15430/JCP.2020.25.3.152 |
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