15-Deoxy-Δ(12,14)-prostaglandin J(2) Induces Epithelial-to-mesenchymal Transition in Human Breast Cancer Cells and Promotes Fibroblast Activation

In inflammation-associated carcinogenesis, COX-2 is markedly overexpressed, resulting in accumulation of various prostaglandins. 15-deoxy-Δ(12,14)-prostaglandin J(2) (15d-PGJ(2)) is one of the terminal products of COX-2-catalyzed arachidonic acid catabolism with oncogenic potential. Epithelial-to-me...

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Detalhes bibliográficos
Publicado no:J Cancer Prev
Main Authors: Choi, Jeehye, Suh, Jin-Young, Kim, Do-Hee, Na, Hye-Kyung, Surh, Young-Joon
Formato: Artigo
Idioma:Inglês
Publicado em: Korean Society of Cancer Prevention 2020
Assuntos:
Review
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7523036/
https://ncbi.nlm.nih.gov/pubmed/33033709
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15430/JCP.2020.25.3.152
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