15-Deoxy-Δ(12,14)-prostaglandin J(2) Upregulates VEGF Expression via NRF2 and Heme Oxygenase-1 in Human Breast Cancer Cells

There is a plethora of evidence to support that inflammation is causally linked to carcinogenesis. Cyclooxygenase-2 (COX-2), a rate-limiting enzyme in the biosynthesis of prostaglandins, is inappropriately overexpressed in various cancers and hence recognized as one of the hallmarks of chronic infla...

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Bibliographische Detailangaben
Veröffentlicht in:Cells
Hauptverfasser: Kim, Eun-Hee, Kim, Su-Jung, Na, Hye-Kyung, Han, Wonshik, Kim, Nam-Jung, Suh, Young-Ger, Surh, Young-Joon
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2021
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8002112/
https://ncbi.nlm.nih.gov/pubmed/33801351
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells10030526
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