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Induction of heme oxygenase-1 in normal and malignant B lymphocytes by 15-deoxy-Δ(12, 14)-prostaglandin J(2) requires Nrf2

Heme-oxygenase-1 (HO-1) is induced in response to oxidative stress and is believed to be a cytoprotective and anti-inflammatory enzyme. It is unknown whether normal or malignant human B lineage cells express HO-1. 15-deoxy-Δ(12, 14)-prostaglandin J(2) (15d-PGJ(2)) is an interesting electrophilic lip...

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Autors principals: Bancos, Simona, Baglole, Carolyn J., Rahman, Irfan, Phipps, Richard P.
Format: Artigo
Idioma:Inglês
Publicat: 2009
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3117258/
https://ncbi.nlm.nih.gov/pubmed/20064636
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cellimm.2009.12.003
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