Enhancing efficacy of gemcitabine in pancreatic patient-derived xenograft mouse models

Gemcitabine (Gem), a nucleoside analog, is a preferred choice of treatment for pancreatic cancer (PCa) and often used in combination therapy against wide range of solid tumors. It is known to be rapidly inactivated in blood by cytidine deaminase. The objective of the study was to improve the systemi...

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Vydáno v:Int J Pharm X
Hlavní autoři: Inkoom, Andriana, Ndemazie, Nkafu, Affram, Kevin, Smith, Taylor, Zhu, Xue, Underwood, Patrick, Krishnan, Sunil, Ofori, Edward, Han, Bo, Trevino, Jose, Agyare, Edward
Médium: Artigo
Jazyk:Inglês
Vydáno: Elsevier 2020
Témata:
Research Paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7522377/
https://ncbi.nlm.nih.gov/pubmed/33015617
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ijpx.2020.100056
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