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Pharmacokinetic, biodistribution and therapeutic efficacy of 5-fluorouracil-loaded pH-sensitive PEGylated liposomal nanoparticles in HCT-116 tumor bearing mouse

The objective of the study was to investigate the pharmacokinetics and efficacy of 5-FU entrapped pH-sensitive liposomal nanoparticles with surface-modified anti-epidermal growth factor receptor (EGFR) antibody (pHLNps-5-FU) delivery system. Cytotoxicity of 5-FU and pHLNps-5-FU was determined in vit...

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Bibliografiske detaljer
Udgivet i:J Nat Sci
Main Authors: Udofot, Ofonime, Affram, Kevin, Smith, Taylor, Tshabe, Bulumko, Krishnan, Sunil, Sachdeva, Mandip, Agyare, Edward
Format: Artigo
Sprog:Inglês
Udgivet: 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4869888/
https://ncbi.nlm.nih.gov/pubmed/27200415
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