Enhancing efficacy of gemcitabine in pancreatic patient-derived xenograft mouse models

Gemcitabine (Gem), a nucleoside analog, is a preferred choice of treatment for pancreatic cancer (PCa) and often used in combination therapy against wide range of solid tumors. It is known to be rapidly inactivated in blood by cytidine deaminase. The objective of the study was to improve the systemi...

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Bibliografiske detaljer
Udgivet i:Int J Pharm X
Main Authors: Inkoom, Andriana, Ndemazie, Nkafu, Affram, Kevin, Smith, Taylor, Zhu, Xue, Underwood, Patrick, Krishnan, Sunil, Ofori, Edward, Han, Bo, Trevino, Jose, Agyare, Edward
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier 2020
Fag:
Research Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7522377/
https://ncbi.nlm.nih.gov/pubmed/33015617
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ijpx.2020.100056
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