Enhancing efficacy of gemcitabine in pancreatic patient-derived xenograft mouse models

Gemcitabine (Gem), a nucleoside analog, is a preferred choice of treatment for pancreatic cancer (PCa) and often used in combination therapy against wide range of solid tumors. It is known to be rapidly inactivated in blood by cytidine deaminase. The objective of the study was to improve the systemi...

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Detalhes bibliográficos
Publicado no:Int J Pharm X
Main Authors: Inkoom, Andriana, Ndemazie, Nkafu, Affram, Kevin, Smith, Taylor, Zhu, Xue, Underwood, Patrick, Krishnan, Sunil, Ofori, Edward, Han, Bo, Trevino, Jose, Agyare, Edward
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2020
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7522377/
https://ncbi.nlm.nih.gov/pubmed/33015617
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ijpx.2020.100056
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