Mechanisms of inside-out signaling of the high affinity IgG-receptor FcγRI

Fc receptors (FcR) are an important bridge between the innate and adaptive immune system. Fc gamma receptor I (FcγRI, CD64), the high affinity receptor for immunoglobulin G (IgG), plays roles in inflammation, autoimmune responses, and immunotherapy. Stimulation of myeloid cells with cytokines, such...

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Publicado en:Sci Signal
Main Authors: Brandsma, Arianne M., Schwartz, Samantha L., Wester, Michael J., Valley, Christopher C., Blezer, Gittan L.A., Vidarsson, Gestur, Lidke, Keith A., Broeke, Toine ten, Lidke, Diane S., Leusen, Jeanette H.W.
Formato: Artigo
Idioma:Inglês
Publicado: 2018
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7521114/
https://ncbi.nlm.nih.gov/pubmed/30042128
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scisignal.aaq0891
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