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Effects of a monocarboxylate transport 1 inhibitor, AZD3965, on retinal and visual function in the rat
BACKGROUND AND PURPOSE: Inhibition of monocarboxylate transport 1 (MCT1) is of interest in targeting highly glycolytic tumours. However, MCT1 is expressed in retina, and so inhibition of MCT1 could affect retinal function. EXPERIMENTAL APPROACH: AZD3965, an MCT1 inhibitor selected for clinical devel...
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| Publicado no: | Br J Pharmacol |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
John Wiley and Sons Inc.
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7520442/ https://ncbi.nlm.nih.gov/pubmed/32833237 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.15239 |
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