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Potential New Cancer Immunotherapy: Anti-CD47-SIRPα Antibodies

CD47 belongs to immunoglobulin superfamily and is widely expressed on the surface of cell membrane, while another transmembrane protein SIRPα is restricted to the surface of macrophages, dendritic cells, and nerve cells. As a cell surface receptor and ligand, respectively, CD47 and SIRPα interact to...

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Publicat a:Onco Targets Ther
Autors principals: Lu, Quansheng, Chen, Xi, Wang, Shan, Lu, Yu, Yang, Chunsheng, Jiang, Guan
Format: Artigo
Idioma:Inglês
Publicat: Dove 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7520119/
https://ncbi.nlm.nih.gov/pubmed/33061420
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/OTT.S249822
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