Anti‐human SIRPα antibody is a new tool for cancer immunotherapy

Interaction of signal regulatory protein α (SIRPα) expressed on the surface of macrophages with its ligand CD47 expressed on target cells negatively regulates phagocytosis of the latter cells by the former. We recently showed that blocking Abs to mouse SIRPα enhanced both the Ab‐dependent cellular p...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Cancer Sci
Prif Awduron: Murata, Yoji, Tanaka, Daisuke, Hazama, Daisuke, Yanagita, Tadahiko, Saito, Yasuyuki, Kotani, Takenori, Oldenborg, Per‐Arne, Matozaki, Takashi
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: John Wiley and Sons Inc. 2018
Pynciau:
Original Articles
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5980332/
https://ncbi.nlm.nih.gov/pubmed/29473266
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cas.13548
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