Anti‐human SIRPα antibody is a new tool for cancer immunotherapy

Interaction of signal regulatory protein α (SIRPα) expressed on the surface of macrophages with its ligand CD47 expressed on target cells negatively regulates phagocytosis of the latter cells by the former. We recently showed that blocking Abs to mouse SIRPα enhanced both the Ab‐dependent cellular p...

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發表在:Cancer Sci
Main Authors: Murata, Yoji, Tanaka, Daisuke, Hazama, Daisuke, Yanagita, Tadahiko, Saito, Yasuyuki, Kotani, Takenori, Oldenborg, Per‐Arne, Matozaki, Takashi
格式: Artigo
語言:Inglês
出版: John Wiley and Sons Inc. 2018
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Original Articles
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5980332/
https://ncbi.nlm.nih.gov/pubmed/29473266
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cas.13548
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