Anti-SIRPα antibodies as a potential new tool for cancer immunotherapy

Tumor cells are thought to evade immune surveillance through interaction with immune cells. Much recent attention has focused on the modification of immune responses as a basis for new cancer treatments. SIRPα is an Ig superfamily protein that inhibits phagocytosis in macrophages upon interaction wi...

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Detalhes bibliográficos
Publicado no:JCI Insight
Main Authors: Yanagita, Tadahiko, Murata, Yoji, Tanaka, Daisuke, Motegi, Sei-ichiro, Arai, Eri, Daniwijaya, Edwin Widyanto, Hazama, Daisuke, Washio, Ken, Saito, Yasuyuki, Kotani, Takenori, Ohnishi, Hiroshi, Oldenborg, Per-Arne, Garcia, Noel Verjan, Miyasaka, Masayuki, Ishikawa, Osamu, Kanai, Yae, Komori, Takahide, Matozaki, Takashi
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2017
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5214103/
https://ncbi.nlm.nih.gov/pubmed/28097229
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.89140
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