Anti-SIRPα antibodies as a potential new tool for cancer immunotherapy

Tumor cells are thought to evade immune surveillance through interaction with immune cells. Much recent attention has focused on the modification of immune responses as a basis for new cancer treatments. SIRPα is an Ig superfamily protein that inhibits phagocytosis in macrophages upon interaction wi...

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Опубликовано в: :JCI Insight
Главные авторы: Yanagita, Tadahiko, Murata, Yoji, Tanaka, Daisuke, Motegi, Sei-ichiro, Arai, Eri, Daniwijaya, Edwin Widyanto, Hazama, Daisuke, Washio, Ken, Saito, Yasuyuki, Kotani, Takenori, Ohnishi, Hiroshi, Oldenborg, Per-Arne, Garcia, Noel Verjan, Miyasaka, Masayuki, Ishikawa, Osamu, Kanai, Yae, Komori, Takahide, Matozaki, Takashi
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Clinical Investigation 2017
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Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5214103/
https://ncbi.nlm.nih.gov/pubmed/28097229
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.89140
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