Anti-SIRPα antibodies as a potential new tool for cancer immunotherapy

Tumor cells are thought to evade immune surveillance through interaction with immune cells. Much recent attention has focused on the modification of immune responses as a basis for new cancer treatments. SIRPα is an Ig superfamily protein that inhibits phagocytosis in macrophages upon interaction wi...

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Vydáno v:JCI Insight
Hlavní autoři: Yanagita, Tadahiko, Murata, Yoji, Tanaka, Daisuke, Motegi, Sei-ichiro, Arai, Eri, Daniwijaya, Edwin Widyanto, Hazama, Daisuke, Washio, Ken, Saito, Yasuyuki, Kotani, Takenori, Ohnishi, Hiroshi, Oldenborg, Per-Arne, Garcia, Noel Verjan, Miyasaka, Masayuki, Ishikawa, Osamu, Kanai, Yae, Komori, Takahide, Matozaki, Takashi
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Clinical Investigation 2017
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5214103/
https://ncbi.nlm.nih.gov/pubmed/28097229
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.89140
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