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Roles of Src family kinase, Ras, and mTOR signaling in intestinal epithelial homeostasis and tumorigenesis

The turnover of intestinal epithelial cells (IECs) is relatively rapid (3‐5 days in mouse and human), and this short existence and other aspects of the homeostasis of IECs are tightly regulated by various signaling pathways including Wnt‐β‐catenin signaling. Dysregulation of IEC homeostasis likely c...

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Bibliographic Details
Published in:Cancer Sci
Main Authors: Matozaki, Takashi, Kotani, Takenori, Murata, Yoji, Saito, Yasuyuki
Format: Artigo
Language:Inglês
Published: John Wiley and Sons Inc. 2020
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7780047/
https://ncbi.nlm.nih.gov/pubmed/33073467
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cas.14702
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