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Roles of Src family kinase, Ras, and mTOR signaling in intestinal epithelial homeostasis and tumorigenesis

The turnover of intestinal epithelial cells (IECs) is relatively rapid (3‐5 days in mouse and human), and this short existence and other aspects of the homeostasis of IECs are tightly regulated by various signaling pathways including Wnt‐β‐catenin signaling. Dysregulation of IEC homeostasis likely c...

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Bibliografski detalji
Izdano u:Cancer Sci
Glavni autori: Matozaki, Takashi, Kotani, Takenori, Murata, Yoji, Saito, Yasuyuki
Format: Artigo
Jezik:Inglês
Izdano: John Wiley and Sons Inc. 2020
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7780047/
https://ncbi.nlm.nih.gov/pubmed/33073467
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cas.14702
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