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Roles of Src family kinase, Ras, and mTOR signaling in intestinal epithelial homeostasis and tumorigenesis

The turnover of intestinal epithelial cells (IECs) is relatively rapid (3‐5 days in mouse and human), and this short existence and other aspects of the homeostasis of IECs are tightly regulated by various signaling pathways including Wnt‐β‐catenin signaling. Dysregulation of IEC homeostasis likely c...

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Detalhes bibliográficos
Publicado no:Cancer Sci
Main Authors: Matozaki, Takashi, Kotani, Takenori, Murata, Yoji, Saito, Yasuyuki
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7780047/
https://ncbi.nlm.nih.gov/pubmed/33073467
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cas.14702
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