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Potential New Cancer Immunotherapy: Anti-CD47-SIRPα Antibodies

CD47 belongs to immunoglobulin superfamily and is widely expressed on the surface of cell membrane, while another transmembrane protein SIRPα is restricted to the surface of macrophages, dendritic cells, and nerve cells. As a cell surface receptor and ligand, respectively, CD47 and SIRPα interact to...

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Detalhes bibliográficos
Publicado no:Onco Targets Ther
Main Authors: Lu, Quansheng, Chen, Xi, Wang, Shan, Lu, Yu, Yang, Chunsheng, Jiang, Guan
Formato: Artigo
Idioma:Inglês
Publicado em: Dove 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7520119/
https://ncbi.nlm.nih.gov/pubmed/33061420
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/OTT.S249822
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