Characterization of BRCA1-deficient premalignant tissues and cancers identifies Plekha5 as a tumor metastasis suppressor

Single-cell whole-exome sequencing (scWES) is a powerful approach for deciphering intratumor heterogeneity and identifying cancer drivers. So far, however, simultaneous analysis of single nucleotide variants (SNVs) and copy number variations (CNVs) of a single cell has been challenging. By analyzing...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Liu, Jianlin, Adhav, Ragini, Miao, Kai, Su, Sek Man, Mo, Lihua, Chan, Un In, Zhang, Xin, Xu, Jun, Li, Jianjie, Shu, Xiaodong, Zeng, Jianming, Zhang, Xu, Lyu, Xueying, Pardeshi, Lakhansing, Tan, Kaeling, Sun, Heng, Wong, Koon Ho, Deng, Chuxia, Xu, Xiaoling
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7519681/
https://ncbi.nlm.nih.gov/pubmed/32978388
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-18637-9
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados