HuR promotes miRNA-mediated upregulation of NFI-A protein expression in MDSCs during murine sepsis

Myeloid-derived suppressor cells (MDSCs) contribute to high mortality rates during sepsis, but how sepsis induces MDSCs is unclear. Previously we reported that microRNA (miR)-21 and miR-181b reprogram MDSCs in septic mice by increasing levels of DNA binding transcription factor, nuclear factor 1 (NF...

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Detalhes bibliográficos
Publicado no:Mol Immunol
Main Authors: Bah, Isatou, Alkhateeb, Tuqa, Kumbhare, Ajinkya, Youssef, Dima, Yao, Zhi, Hawkins, Gregory A., McCall, Charles E., El Gazzar, Mohamed
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7519576/
https://ncbi.nlm.nih.gov/pubmed/32474254
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molimm.2020.04.014
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