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S100A9 maintains myeloid-derived suppressor cells in chronic sepsis by inducing miR-21 and miR-181b

Myeloid-derived suppressor cells (MDSC) expand during sepsis, suppress both innate and adaptive immunity, and promote chronic immunosuppression, which characterizes the late/chronic phase of sepsis. We previously reported that the transcription factors Stat3 and C/EBPβ synergize to induces the expre...

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Detalhes bibliográficos
Publicado no:Mol Immunol
Main Authors: Alkhateeb, Tuqa, Kumbhare, Ajinkya, Bah, Isatou, Youssef, Dima, Yao, Zhi Q., McCall, Charles E., El Gazzar, Mohamed
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6646085/
https://ncbi.nlm.nih.gov/pubmed/31078118
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molimm.2019.04.019
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