Intracellular S100A9 Promotes Myeloid-Derived Suppressor Cells during Late Sepsis

Myeloid precursor cell reprogramming into a myeloid-derived suppressor cell (MDSC) contributes to high mortality rates in mouse and human sepsis. S100A9 mRNA and intracellular protein levels increase during early sepsis and remain elevated in Gr1(+)CD11b(+) MDSCs after pro-inflammatory sepsis transi...

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Vydáno v:Front Immunol
Hlavní autoři: Dai, Jun, Kumbhare, Ajinkya, Youssef, Dima, McCall, Charles E., El Gazzar, Mohamed
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2017
Témata:
Immunology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5698275/
https://ncbi.nlm.nih.gov/pubmed/29204146
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2017.01565
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