Intracellular S100A9 Promotes Myeloid-Derived Suppressor Cells during Late Sepsis

Myeloid precursor cell reprogramming into a myeloid-derived suppressor cell (MDSC) contributes to high mortality rates in mouse and human sepsis. S100A9 mRNA and intracellular protein levels increase during early sepsis and remain elevated in Gr1(+)CD11b(+) MDSCs after pro-inflammatory sepsis transi...

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Udgivet i:Front Immunol
Main Authors: Dai, Jun, Kumbhare, Ajinkya, Youssef, Dima, McCall, Charles E., El Gazzar, Mohamed
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2017
Fag:
Immunology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5698275/
https://ncbi.nlm.nih.gov/pubmed/29204146
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2017.01565
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