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PD-L1 on dendritic cells attenuates T cell activation and regulates response to immune checkpoint blockade
Immune checkpoint blockade therapies have shown clinical promise in a variety of cancers, but how tumor-infiltrating T cells are activated remains unclear. In this study, we explore the functions of PD-L1 on dendritic cells (DCs), which highly express PD-L1. We observe that PD-L1 on DC plays a criti...
שמור ב:
| הוצא לאור ב: | Nat Commun |
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| Main Authors: | , , , , , , , , , , |
| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
Nature Publishing Group UK
2020
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7518441/ https://ncbi.nlm.nih.gov/pubmed/32973173 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-18570-x |
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