PD-L1 on host cells is essential for PD-L1 blockade–mediated tumor regression

Programmed death–ligand 1 (PD-L1) expression on tumor cells is essential for T cell impairment, and PD-L1 blockade therapy has shown unprecedented durable responses in several clinical studies. Although higher expression of PD-L1 on tumor cells is associated with a better immune response after Ab bl...

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Detaylı Bibliyografya
Yayımlandı:J Clin Invest
Asıl Yazarlar: Tang, Haidong, Liang, Yong, Anders, Robert A., Taube, Janis M., Qiu, Xiangyan, Mulgaonkar, Aditi, Liu, Xin, Harrington, Susan M., Guo, Jingya, Xin, Yangchun, Xiong, Yahong, Nham, Kien, Silvers, William, Hao, Guiyang, Sun, Xiankai, Chen, Mingyi, Hannan, Raquibul, Qiao, Jian, Dong, Haidong, Peng, Hua, Fu, Yang-Xin
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Clinical Investigation 2018
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5785245/
https://ncbi.nlm.nih.gov/pubmed/29337303
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI96061
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