Increased Protein Stability and Interleukin-2 Production of a LAT(G131D) Variant With Possible Implications for T Cell Anergy

The adaptor LAT plays a crucial role in the transduction of signals coming from the TCR/CD3 complex. Phosphorylation of some of its tyrosines generates recruitment sites for other cytosolic signaling molecules. Tyrosine 132 in human LAT is essential for PLC-γ activation and calcium influx generation...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Front Cell Dev Biol
Main Authors: Arbulo-Echevarria, Mikel M., Vico-Barranco, Inmaculada, Narbona-Sánchez, Isaac, García-Cózar, Francisco, Miazek, Arkadiusz, Aguado, Enrique
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020
Assuntos:
Cell and Developmental Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7517355/
https://ncbi.nlm.nih.gov/pubmed/33042995
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcell.2020.561503
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados