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Phorbol ester-mediated re-expression of endogenous LAT adapter in J.CaM2 cells: a model for dissecting drivers and blockers of LAT transcription

Linker for activation of T cells (LAT) is a raft-associated, transmembrane adapter protein critical for T-cell development and function. LAT expression is transiently upregulated upon T-cell receptor (TCR) engagement, but molecular mechanisms conveying TCR signaling to enhanced LAT transcription are...

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Detalhes bibliográficos
Publicado no:Genes Immun
Main Authors: Marek-Bukowiec, K, Aguado, E, Miazek, A
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4972999/
https://ncbi.nlm.nih.gov/pubmed/27278128
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/gene.2016.25
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