Structural insight into the binding of human galectins to corneal keratan sulfate, its desulfated form and related saccharides

Glycosaminoglycan chains of keratan sulfate proteoglycans appear to be physiologically significant by pairing with tissue lectins. Here, we used NMR spectroscopy and molecular dynamics (MD) simulations to characterize interactions of corneal keratan sulfate (KS), its desulfated form, as well as di-,...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Pubblicato in:Sci Rep
Autori principali: Miller, Michelle C., Cai, Chao, Wichapong, Kanin, Bhaduri, Sayantan, Pohl, Nicola L. B., Linhardt, Robert J., Gabius, Hans-Joachim, Mayo, Kevin H.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2020
Soggetti:
Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7515912/
https://ncbi.nlm.nih.gov/pubmed/32973213
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-72645-9
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi