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Inferring efficiency of translation initiation and elongation from ribosome profiling

One of the main goals of ribosome profiling is to quantify the rate of protein synthesis at the level of translation. Here, we develop a method for inferring translation elongation kinetics from ribosome profiling data using recent advances in mathematical modelling of mRNA translation. Our method d...

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Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Main Authors: Szavits-Nossan, Juraj, Ciandrini, Luca
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7515720/
https://ncbi.nlm.nih.gov/pubmed/32821926
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkaa678
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