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HCV IRES manipulates the ribosome to promote the switch from translation initiation to elongation

The hepatitis C virus (HCV) internal ribosome entry site (IRES) drives non-canonical initiation of protein synthesis necessary for viral replication. HCV IRES functional studies have focused on 80S ribosome formation, but have not explored roles after the 80S ribosome is poised at the start codon. H...

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Bibliografiska uppgifter
Huvudupphovsmän: Filbin, Megan E., Vollmar, Breanna S., Shi, Dan, Gonen, Tamir, Kieft, Jeffrey S.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2012
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Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3864654/
https://ncbi.nlm.nih.gov/pubmed/23262488
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb.2465
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