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HCV IRES manipulates the ribosome to promote the switch from translation initiation to elongation

The hepatitis C virus (HCV) internal ribosome entry site (IRES) drives non-canonical initiation of protein synthesis necessary for viral replication. HCV IRES functional studies have focused on 80S ribosome formation, but have not explored roles after the 80S ribosome is poised at the start codon. H...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Filbin, Megan E., Vollmar, Breanna S., Shi, Dan, Gonen, Tamir, Kieft, Jeffrey S.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2012
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3864654/
https://ncbi.nlm.nih.gov/pubmed/23262488
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb.2465
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