Role of Fluorophore Charge on the In Vivo Optical Imaging Properties of Near-Infrared Cyanine Dye/Monoclonal Antibody Conjugates

Near-infrared (NIR) fluorophores have several advantages over visible-light fluorophores, including superior light penetration in tissue and lower autofluorescence. We recently demonstrated that a new class of NIR cyanine dyes containing a novel C4’-O-arlkyl linker exhibit greater chemical stability...

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Udgivet i:Bioconjug Chem
Main Authors: Sato, Kazuhide, Gorka, Alexander P., Nagaya, Tadanobu, Michie, Megan S., Nani, Roger R., Nakamura, Yuko, Coble, Vince L., Vasalatiy, Olga V., Swenson, Rolf E., Choyke, Peter L., Schnermann, Martin J., Kobayashi, Hisataka
Format: Artigo
Sprog:Inglês
Udgivet: 2015
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7512024/
https://ncbi.nlm.nih.gov/pubmed/26444497
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.bioconjchem.5b00492
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