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Molecularly Targeted Cancer Combination Therapy with Near Infrared Photoimmunotherapy and Near Infrared Photo-release with Duocarmycin-antibody Conjugate

Near infrared photoimmunotherapy (NIR-PIT) is a highly selective tumor treatment that employs an antibody-photo-absorber conjugate (APC). However, the effect of NIR-PIT can be enhanced when combined with other therapies. NIR photocaging groups, based on the heptamethine cyanine scaffold, have been d...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Mol Cancer Ther
Hauptverfasser: Nagaya, Tadanobu, Gorka, Alexander P., Nani, Roger R., Okuyama, Shuhei, Ogata, Fusa, Maruoka, Yasuhiro, Choyke, Peter L., Schnermann, Martin J., Kobayashi, Hisataka
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2017
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5935585/
https://ncbi.nlm.nih.gov/pubmed/29237807
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1535-7163.MCT-17-0851
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